SINCE The second world war, medical science has progressed to a stage where competitive medications are around to treat the identical ailment in numerous people. It’s not nearly brands (which is a trade issue) but generic drugs (which is a scientific issue). Within this report, we shall look at the various factors that decide picking a a specific drug.
Safety: The subsequent sub-criteria should be considered within the criterion of safety:
* Acute therapeutic index: If your patient’s condition is acute, how effective is often a particular drug even though it’s certain side-effects provided that the acuteness from the condition is lowered? Example: narcotic pain-killers are amazing in healing pain but feature the opportunity side-effect of addiction.
* Long-term safety: http://medicationdirectory.com may be safe in short-term treatment, so how safe it’s in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but tend to have undesirable effects in case there is prolonged use.
* Drug-drug interaction risk: Drugs are chemicals, and many chemicals reply to develop a different chemical, which has an effect that may harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to produce a new condition that warrants separate treatment.
Drug-drug interaction risk is of two kinds:
· Pharmacokinetic: In this type of drug-drug interaction, two drugs, independent of the other person, have certain effects using one or even more body processes (e.g., metabolism) that affects the performance from the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) depends on for its metabolism. This leads to a boost in the side-effects of Lexapro.
· Pharmacodynamic: Here, 2 or more drugs actually create the same impact on the identical organ, thus improving the total, added effect. Example: Lexapro has certain side-effects such as drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the two drugs are more serious.
Tolerability: A drug may be effective but not tolerable by all patients. Example: Allergies to certain drugs in most people. Short-term and long-term tolerability need to be looked at. Efficacy: A drug isn’t equally efficient at all patients. For example, some patients with depression or panic attacks experience rest from escitalopram, but there are numerous that do not, who therefore need to be prescribed another anti-depressant. The speed of start of therapeutic action is an important factor to be considered too.
Cost: Cost does not necessarily mean the price tag on acquisition of a certain medicine alone. It must also cover the price tag on treatments for a complication that may arise while using another drug. Example: In the individual that insists on taking alcohol and yet has to be treated for depression is generally administered an SSRI drug since these drugs don’t potentiate the effects of alcohol, whereas another band of anti-depressants (such as tricyclics) might cause a whole new overuse injury in such patients, which may require a various and expensive treatment. Therefore, it’s preferable to prescribe the more costly escitalopram as opposed to a cheaper tricyclic in these patients.
Simplicity of treatment: Most effective mode of administration is preferred. When there is a selection between a shot and oral administration, rogues is preferred if the efficacy of the two modes can be compared. Or, local application is chosen over the oral route where possible; e.g., antibiotic treatments for eye infections. Dosage and frequency of administration too are a key factor to make a decision simple treatment.
For more details about http://medicationdirectory.com see our web portal: click