The Criteria For choosing Medication For any Patient

SINCE World War II, medical science has progressed to some stage where competitive medications are for sale to treat the same ailment in different people. This is simply not just about brands (which is a trade issue) but generic drugs (which is a scientific issue). With this report, we shall consider the various factors that decide the selection of a specific drug.

Safety: The following sub-criteria has to be considered under the criterion of safety:

* Acute therapeutic index: In the event the patient’s condition is acute, how effective is often a particular drug even when it’s certain side-effects providing the acuteness from the condition is lowered? Example: narcotic pain-killers are incredible in healing pain but include the potential side-effect of addiction.

* Long-term safety: medication could possibly be safe in short-term treatment, but how safe it is in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but tend to have undesirable effects in the case of prolonged use.

* Drug-drug interaction risk: Medicine is chemicals, and lots of chemicals respond to develop a different chemical, which has an effect which could harm the person or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to create a new condition that warrants separate treatment.

Drug-drug interaction risk is of two sorts:

· Pharmacokinetic: In this type of drug-drug interaction, two drugs, independent of each other, have certain effects one or even more body processes (e.g., metabolism) that affects the performance from the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) is determined by for its metabolism. This makes a boost in the side-effects of Lexapro.

· Pharmacodynamic: Here, 2 or more drugs actually make the same influence on the same organ, thus helping the total, added effect. Example: Lexapro has certain side-effects including drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of both the medicines are more intense.

Tolerability: A medicine could possibly be effective but not tolerable by all patients. Example: Allergies to specific drugs in most people. Short-term and long-term tolerability must be taken into account. Efficacy: A medicine is just not equally great at all patients. By way of example, some patients with depression or anxiety attacks experience rest from escitalopram, but there are many who don’t, who therefore must be prescribed another anti-depressant. The rate of oncoming of therapeutic action is an important the answer to be looked at too.

Cost: Cost does not always mean the expense of purchase of some medicine alone. It will also cover the expense of management of a complication which could arise while using another drug. Example: Inside a one who insists on taking alcohol yet should be treated for depression is generally administered an SSRI drug since these drugs don’t potentiate the end results of alcohol, whereas another gang of anti-depressants (including tricyclics) can cause a new problem in such patients, which will need a various and expensive treatment. Therefore, it’s safer to prescribe the more costly escitalopram instead of a cheaper tricyclic such patients.

Simple treatment: The best mode of administration is preferred. If you find an alternative between a shot and oral administration, the latter is preferred in the event the efficacy of both the modes is analogous. Or, local application is chosen over the oral route where possible; e.g., antibiotic management of eye infections. Dosage and frequency of administration too are an important factor to determine simplicity of treatment.
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